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What are MDMA’s effects on the brain? MDMA affects the brain by increasing the activity of at least three neurotransmitters (the chemical messengers of brain cells): serotonin, dopamine, and norepinephrine. Like other amphetamines, MDMA enhances release of these neurotransmitters and/or blocks their reuptake, resulting in increased neurotransmitter levels within the synaptic cleft (the space between the neurons …

What are MDMA’s effects on the brain? MDMA affects the brain by increasing the activity of at least three neurotransmitters (the chemical messengers of brain cells): serotonin, dopamine, and norepinephrine. Like…